الفهرس 
Epidemology of High Grade GliomaOnly 14 pages are availabe for public view
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Abstract
In our study steroid dependency (failure to taper steroid after radiotherapy) was a predictor for poor survival in both conventional and hypofractionated arm and with statistically significant difference on those patients nondependent on steroids.
In our study (clinical symptoms at presentation) in each arm failed to correlate to survival except the seizure which was significant associated with lower survival in conventional arm only. Finally, our study failed to identify tumor size as prognostic factor for GBM.
Our recommendations is to adopt short hypofractionated radiotherapy in management of elderly and poor performance patients with high grade glioma as the hypofractionated conformal radiotherapy was found to be as effective as the conventional radiotherapy with no severe adverse effects. Especially in patients over 70 years old in whom survival was statistically significant better than with conventional arm.
Considering the benefit of the short-course regimen in terms of time sparing for patients, and for radiation oncology centers, which are often overloaded by long patient waiting lists, the hypofractionated radiotherapy should be evaluated among younger and good performance patients.
Studies with greater number of patients are advised to realistic evaluation of glioblastoma prognostic factors. And we recommend further study about hypofractionated radiotherapy with temozolomide.