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Abstract Introduction: Anemia is a global public health problem affecting both developing and developed countries with major consequences for human health as well as social and economic development. It occurs at all stages of the life cycle. The most significant contributor to the onset of anemia is iron deficiency. Aim of the Work: To evaluate the iron status in obese Egyptian females in comparison to normal weight females. Subjects and Methods: This study was conducted on 44 obese adult female patients attending the outpatient clinics in the National Nutrition Institute (NNI). Forty four healthy adult females’ with matched age were included in the study as control group. Informed written consent was taken from both groups. Results: This is a case control study that was conducted on 88 adult female; 44 adult obese female patients their age ranged from 18-53 years with mean age of (31.55±9.83) years and BMI mean (38.81± 4.79) kg/m², and 44 normal weight healthy controls their age ranged from 18-50 years with mean age of (25.41±7.40) years and BMI mean (21.58 ± 2.19) kg/m². Conclusion: Obesity is worldwide disease that affect all ages especially women. It is considered as low inflammatory disease which increases CRP and affects iron profile by decreasing serum iron and TSI and increasing ferritin level. The exact mechanism of the relationship between obesity and IDA could not be determined. Recommendations: Health communication should be strengthened through primary health care and media to prevent iron deficiency anemia and obesity. |