الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
The worldwide incidence of obesity is reaching alarming proportions globally. The problem lies not only in obesity, but also in the associated metabolic derangements, collectively known as metabolic syndrome. Surgery has proved to be the best way to control this epidemic through what is known as (bariatric interventions). Currently, Roux-en-Y Gastric Bypass (RYGB) and sleeve gastrectomy (SG) are the most common surgical interventions worldwide in this field. The best way to compared both procedures is through a prospective randomized trial (RCT).
This RCT was performed in Sachsenhausen Hospital (a bariatric surgery centre of excellence, Frankfurt am Main, Germany) and in Sana Clinic (a bariatric surgery centre of excellence, Offenbach, Germany). The study included 80 patients who were assigned into one of two equal groups (40 patients); LRYGB group and LSG group. Postoperative follow-up for at 6 and 12 months was performed for all patients. Baseline demographic data and co-morbidities between LRYGB and LSG groups showed no significant difference. At baseline, mean weight was 136.5 ± 12.2 kg in the LRYGB group and 137.7 ± 11.9 kg in the LSG group respectively. Mean basal BMI was respectively 46.2 ± 6.6 kg/m2 vs. 45.1 ± 5.7 kg/m2. At 6 and 12 months postoperatively, % EWL reached 41.2 ± 6.7 % vs. 40.9 ± 6.8 % and 68.9 ± 2.6 % vs. 66.9 ± 2 in the LRYGB and LSG groups respectively (not significant). The mean operative duration was significantly longer in the LRYGB group (56.8±9 vs. 47±7.4 min). The mean number of fired cartridges was also significantly more in the LRYGB group (6.4±0.5 vs.5.3±0.5). All procedures were completed laparoscopically and all patients were discharged om the 5th day. Staple line bleeding was encountered in one patient after LSG (not significant). QOL improved significantly in both groups, but no interprocedural difference. Mean preoperative MAQOL II was -2.1 ± 0.6 vs. -2.1 ± 0.5. Mean postoperative BAROS at 6 and 12 months was 4.5 ± 0.1 vs. 4.3 ± 0.5 and 6.48 ± 0.1 vs. 6.1 ±0.9 in the LRYGB and LSG groups respectively.