الفهرس 
? EncephalitisOnly 14 pages are availabe for public view
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Abstract
Initial investigation include CT of the brain with contrast, LP with cell count, protein, glucose (and serum glucose), viral screen (especially HSV, HHV-6), acid-alcohol fast bacilli (AAFB) smear, bacterial and mycobacterium culture. CSF and serum examination for anti-neuronal antibodies, paraneoplastic proteins and antibodies against neuronal cell membrane antigen is also essential. An MRI brain is mandatory, could show hyperintense signal in the medial aspect of the temporal lobes which are often asymmetric, and sometimes unilateral.
Our study aimed to asses quantitatively GAD antibody in CSF and serum samples in a cohort study of children presenting with acute encephalitis (filling the clinical criteria) by Enzyme-linked immunosorbent assay (ELISA) technique.
The study was performed on 50 children complaining of acute encephalitis, where 32 patient were male, and 18 were female, median age was 24 (12-60) month, range (6-144) month old.
History taking and clinical examination in details were done to all patients.
Laboratory evaluation by CBC, CRP, Lumbar puncture, CSF analysis, measuring GAD antibody titer in serum and CSF, EEG and neuroimaging. Also clinical and laboratory data obtained upon admission were analyzed as comparisons of antiglutamic acid decarboxylase antibody-high titer patients with antiglutamic acid decarboxylase antibody-low titer patients. The data included sex, age, seizure, electroencephalogram findings, neuroimaging studies, and cerebrospinal fluid leukocyte and protein measurements. The associations between each of these variables.