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Abstract Doxorubicin (Dox) is one of the most efficient anticancer drugs currently in clinical but it causes cardiomyopathy. The aim of this study was to evaluate the possible protective effect of hesperidin (Hsp) and / or vitamin E (Vit.E) against Dox –induced cardiomyopathy. Rats were divided into five groups: control group (I); group II: rats injected with Dox, group (III); rats injected with Dox and administrated with Hsp, group IV: rats injected with Dox and administrated with Vit.E, group V: rats injected with Dox and administrated with Hsp and Vit.E. |