الفهرس 
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Abstract
Formerly called toxemia, preeclampsia is a condition that pregnant women develop. It is marked by high blood pressure in women who have previously not experienced high blood pressure before. Preeclamptic women will have a high level of protein in their urine and often also have swelling in the feet, legs, and hands. This condition usually appears late in pregnancy, generally after the 20 week mark, although it can occur earlier. Calprotectin is calcium-binding protein which can be found in the cytosol of neutrophils and myelomonocytic cells, plays a role in various physiological functions such as inflammatory processes and antiproliferation of cells, and in the neutrophil defense against bacterial infections.
The aim of study was to evaluate the maternal blood level of calprotectin in cases of mild and severe preeclampsia compared to normotensive pregnancy.
The study included 84 pregnant females attending El Shatby Maternity University Hospital, after taking their consent for participation of this work.
Cases will be divided into three groups
• group (A): includes 28 cases of normotensive pregnant females.
• group (B): Includes 28 cases of pregnant females with mild preeclampsia.
• Group(C): includes 28 cases of pregnant females with severe preeclampsia.
Methods: after history, examination and ultrasound assessment of fetal condition, 5 ml of maternal venous blood were collected, measure the level of serum calprotectin and evaluate results of mild and severe preeclamptic and normotensive pregnant females.
As regard to maternal age, there was statistical significant difference between control group and mild preeclampsia group, between control group and severe preeclampsia group and there was no significant difference between mild and severe preeclampsia groups (p<0.05).
While gestational age between studied groups. Gestational age in mild preeclampsia group ranged from 25-38w, in severe preeclampsia group ranged from 24-38w and in control group ranged from 22-33w. There was statistical significant difference between control group and mild preeclampsia group, between control group and severe preeclampsia group and there was no significant difference between mild and severe preeclampsia groups (p<0.05).
According to platelets between studied groups. Platelets in mild preeclampsia group ranged from 98000-372000, in severe preeclampsia group ranged from 34000-368000 and in control group ranged from 167000-400000.There was no statistical difference between studied groups.
Also, the urea level between studied groups. Urea in mild group ranged from 5-44mg/dl, in severe preeclampsia group ranged from 3-66mg/dl and in control group ranged from 5-43mg/dl. There was no statistical difference between studied groups (p<0.05).
In regards to to creatinine between studied groups. Creatinine in mild preeclampsia group ranged from 0.5-1.10, in severe preeclampsia group ranged from 0.2-1.90 and in control group ranged from 0.2-1.2. There was no significant difference between studied groups (p<0.5).
According to SGOT between studied groups. SGOT in mild preeclampsia group ranged from 12-57, in severe preeclampsia group ranged from 10-394 and in control group ranged from 10-45.There was no significant difference between normotensive group and mild PET group (p<0.05), there was difference between normotensive group and severe PET as (p< 0.001) and