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Abstract Introduction: Trabeculectomy has become the golden standard for filtering surgery of glaucoma since its introduction by Cairns in 1968. Aim of the Study: The aim of this study is to compare between the efficacy of collagen biodegradable matrix and mitomycin C in subscleral trabeculectomy in cases of primary open angle glaucoma. Patients and Methods: This prospective comparative interventional randomized study was performed in the Department of Ophthalmology in Faculty of Medicine of Ain Shams University. Thirty eyes of 22 patients with primary open angle glaucoma (POAG) were assigned randomly to undergo subscleral trabeculectomy (SST). Results: In our study 30 eyes of 22 patients with POAG were assigned randomly to undergo SST. Fifteen eyes underwent trabeculectomy with the application of Ologen (Ologen group) and the other 15 eyes underwent trabeculectomy with the application of MMC (MMC group). Conclusion: In conclusion, our study indicates that trabeculectomy with the application of Ologen is a safe and effective procedure in patients with POAG, but it does not seem to offer any remarkable advantages when compared with trabeculectomy with the application of MMC. |