الفهرس 
Literature survey on 2-hydroxybenzoylhydrazide (2-HBH) complexes
Experimental and Theortical BackgroundOnly 14 pages are availabe for public view
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Abstract
New three Schiff base ligands, (H3L1, H3L2, H3L3) resulting from
condensation of o-acetoacetylphenol with salicylaldehyde hydrazone , 2-
hydroxybenzohydrazide and benzoylhydrazide, respectively were
synthesized. Reactions of the ligands with alkaline earth metals such as:
magnesium(II), calcium(II), strontium(II) and barium(II) in the presence
of LiOH; and some transition metal ions such as chromium(III),
manganese(II), iron(III), cobalt(II), nickel(II), copper(II), zinc(II),
cadmium(II) and dioxouranium(VI) ions yielded mono-, bi- and
trinuclear complexes. The complexes were characterized by elemental,
thermal analyses, IR, electronic, 1H NMR, ESR and mass spectra as well
as conductivity and magnetic susceptibility measurements. Different
geometrical structures were proposed for the metal complexes of the
Schiff base ligands. Molecular orbital calculations were carried out on
the free ligands and their complexes using HyperChem 7.5 program at
semiempirical PM3 level. The calculated structural parameters data are
found to be linearly correlated with some of the experimental data such
as: TGA, IR frequencies and biological activity results. The Schiff base
ligands and some of their complexes showed antibacterial activity
towards some of Gram–positive, Gram–negative bacteria, yeast (C.
albicans) and fungus (A. fumigatus). The antitumor activity of the ligands
H3L1 and H3L2 and their Ni(II) and Cu(II) complexes was investigated
against HepG2 cell line.