الفهرس 
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Abstract
Surgical site infection is a kind of health care related infection which a wound illness occurs following to an invasive surgical process. Aim of study: Compare between uses of chlorhexidine gluconate versus povidone iodine for skin preparation to prevent infection after Cardiothoracic Surgery. Setting of studies: Cardio Thoracic Surgery department at Main Mansura University Hospital. Study Design: Quasi experimental designs comparative following up study. Subjects: 77 patients were selected randomly and divided into two equal groups, 35 patients for each group. Tools: Two tools were used for data collection. Tool1: Patients bio-sociodemographic data contain of two parts. Part 1: Sociodemographic data. Part 2: Patient’s clinical data. Tool 2: Wound infection assessment it involved of three Partitions. Partition 1: Wound assessment. Partition 2: laboratory findings. Partition 3: Side effects of antiseptic solutions. Results: The most side effects of surgical site infection appeared in povidone group more than chlorhexidine group in addition to majority of chlorhexidine group was no growth. Conclusions: the incidence of SSI with povidone iodine more than chlorhexidine group. Recommendations: chlorhexidine gluconate with alcohol should be used to prevent of SSI.