الفهرس 
NEONATAL SEPSISOnly 14 pages are availabe for public view
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Abstract
Abstract
Studies indicate that 30-50% of antibiotics prescribed in hospitals are unnecessary or inappropriate. There is no doubt that overprescribing and mis-prescribing is contributing to the growing challenges posed by Clostridium difficile and antibiotic-resistant bacteria.
The consumption of antibiotics in the Special Neonatal Care Unit remains relatively high despite the introduction of the Hospital Antibiotic Policy.
Overuse of antibiotics results from prescribers failing to appreciate that the use of an antibiotic has microbiologic and ecologic consequences that go beyond the individual, treated patient in the bed. Appropriate educational efforts could deal with these problems, but to date they have not been shown widely effective in improving use. Thus, some have suggested that control measures are needed.
To prevent the abuse or misuse of antibiotics, it is necessary to identify and correct individual and collective actions that contribute to the growing problem of antibiotic resistance.
from our observational study on 51 neonates we found that high rate of change antibiotics with percentage of appropriateness 74.3% means high rate of sepsis with virulent types of organisms which need strict infection control protocol with participation of doctors and nurses. Nurseries should periodically review their bacterial sensitivity pattern and the antibiotic policy.
Also strategy of antibiotic usage in the hospital must be reviewed to implement new antibiotic protocol on base of our results which showed the high resistance pattern was to penicillin and 3rd generation cephalosporins thus indicating that the use of these drugs might be ineffective therefore great caution is required in selection of antibiotic therapy.
Results also showed that prevalent pathogens responsible for late onset sepsis and health care acquired infection were klebsiella, candida and acintobactar which associated mainly with surgical cases followed by klebsiella. Only two organisms showed pan resistant pattern were klebsiela and acintobacter.
Keywords: Antibiotic Policy, NICU, klebsiela, acintobacter, candida, cephalosporins.