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العنوان
Effect of Inhaled Corticosteroids on Small Airways in Newly Diagnosed Asthmatic Patients by Using Impulse Oscillometry/
المؤلف
Hashem,Ahmed Elsayed Monir
هيئة الاعداد
باحث / أحمد السيد منير هاشم
مشرف / شريف البوهي
مشرف / إيمان بدوي
تاريخ النشر
2017
عدد الصفحات
131.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم المناعة والحساسية
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Chest Diseases and Tuberculosis
الفهرس
Only 14 pages are availabe for public view

from 131

from 131

Abstract

Abstract
Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. It is defined by the history of respiratory symptoms such as wheeze, shortness of breath, chest tightness and cough that vary over time and in intensity, together with variable expiratory airflow limitation.
The diagnosis of asthma requires a history or current presence of respiratory signs and symptoms consistent with asthma, combined with the objective demonstration of variable airflow obstruction. Variable airflow obstruction means that the obstruction is not necessarily present at all times, varying with time, exposure to asthma triggers and treatment. A good response to asthma treatment in a patient with a typical history of asthma supports a diagnosis of asthma. However, objective confirmation of the variable airflow obstruction characteristic of asthma, using spirometry or peak expiratory flow monitoring, is required, especially for patients whose response to treatment is suboptimal or whose symptoms are not highly suggestive of asthma.
Results revealed that there was a highly statistically significant improvement as regards the FEV1, FVC, FEV1/FVC and MMEF25-75 at 1 month and 3 months of regular recommended treatment.
In the current study, there was highly statistically significant improvement as regards change in FEV1, FVC, FEV1/FVC and MMEF 25 -75 when comparing 1 day, 1 month and 3 months. Regular use provides progressive improvement over time.
In the current study, there was statistically significant improvement as regards the R5, R20, X5 at 1 month and 3 months of regular recommended treatment.
In the current study, shows that there was statistically significant improvement as regards the R5, R20, X5 at 3 months of regular recommended treatment.
In the current study, both spirometric and IOS parameters were equally sensitive in detecting reversibility of airways obstruction.
In the current study, there was a highly statistically significant improvement as regards change in R5, R20 and X5 at 1 day, 1 month and 3 months.
Keywords: Effect of Inhaled Corticosteroids on Small Airways in Newly Diagnosed Asthmatic Patients by Using Impulse Oscillometry