الفهرس 
Congenital Adrenal HyperplasiaOnly 14 pages are availabe for public view
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Abstract
Introduction: Steroids contribute to elevated cardiovascular diseases partly by changing the levels of lipoproteins that carry cholesterol in blood by increasing levels of LDL and decreasing levels of HDL which may lead to heart attack or stroke, also can cause alteration in cardiac structure such as enlargement and thickening of the left ventricle which impairs normal contraction and relaxation of it (cardiomyopathy) all these may lead to hypertension, cardiac arrhythmias, congestive heart failure, heart attack and sudden cardiac arrest.
Aim Of The Work: This study aims to evaluate echo-cardiographic functions in children with congenital adrenal hyperplasia receiving corticosteroid therapy for a time interval ranging from 2 to 4 years.
Patients And Methods This is a prospective case-control study that included twenty-one with congenital adrenal hyperplasia following-up regularly at the Pediatric Endocrinology Clinic Children Hospital, Ain-Shams University.
Results : This case-control study was conducted on twenty-one Congenital adrenal hyperplasia pediatric patients due to 21-OH deficiency. All patients are diagnosed based on clinical and laboratory basis and are following up regularly at the Pediatric Endocrinology Clinic, Children Hospital, Ain-Shams University.
Summary: Congenital adrenal hyperplasia (CAH) is one of the most frequent congenital endocrine disorders; it comprises autosomal recessive disorders of cortisol biosynthesis in the adrenal gland caused by various enzyme deficiencies. The consequent compensatory rise of ACTH production causes hyperplastic growth of the adrenal glands.
Treatment of CAH aims to reduce excessive androgen secretion by replacing the deficient hormones, where proper treatment with GCs and MCs prevents adrenal crisis and virilization, allowing normal growth and development.