الفهرس | Only 14 pages are availabe for public view |
Abstract UMMARY Older people make up a large and an increasing percentage of the population. As people grow older they are increasingly at risk of falling and consequent injuries. A fall may be the first indication of an undetected illness. The prevention of falls is of major importance because they cause considerable mortality, morbidity and suffering for older people and their families, and incur serious physical, psychological and financial consequences to the patient and also to the society. Although, falls are multi-factorial, medication use is an important risk factor among the different risk factors of falls. This thesis was conducted to assess the relation between medication use and falls among elderly in elderly homes. It was a case control study that included 240 elderly participants (60 years old and above), both males and females who were recruited from Cairo’s elderly home residents, they were divided into three groups: Non fallers, People at risk of falls and fallers. The study showed that mean age of fallers and people at risk of falls was significantly higher than that of non-fallers. Summary 78 Regarding the main issue of the study, It showed a clear significance of the association between falls and medication use among elderly by showing that falls were significantly associated with the use of vasodilators (33.8% of fallers), diuretics (33.8% of fallers), alpha blockers (31.3% of fallers), antipsychotics (31.3% of fallers), sedative hypnotics (26.3% of fallers) and opioids (6.3% of fallers). The current study also showed that there was also a significant association between falls and the recent change in dose of ACEIs, diuretics, insulin and oral hypoglycemics.It also showed that falls were significantly associated with the use 5 drugs or more. As regards the chronic medical disorders among the three studied groups, the current study showed that the most significant association was between falls and IHD (38.8% of fallers). The most significant chronic medical disorder that was associated with increased risk of falls was osteoarthritis (50% of people with TUGT>14). Also, There was a significant association between falls and postural hypotension. Additionally, the current study also identified that falls and increase risk of falls are significantly associated with higher BMI and higher scores of GDS. Summary 79 The current study also showed that falls were significantly associated with functional impairment as measured by ADL & IADL. It showed also a significant association between a lower score of MMSE and the increased risk of falls. Multivariate logistic regression proved that the strongest risk factors that can predict falls were the use of alpha blockers and the use of vasodilators, showing a clear evidence of the significance of the association between falls and medication use among elderly. |