الفهرس 
Contents
Sleep Related Breathing DisordersOnly 14 pages are availabe for public view
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Abstract
This prospective study was conducted at Chest Medicine Department Mansoura University SDB Unit during the period from January 2014 to December 2015, and consisted of 75 patients planning for bariatric surgery, aiming to know prevalence, associated risk factors and possible predictors of sleep related breathing disorders among bariatric populations. So all patients were subjected to: Clinical evaluation especially for symptoms and signs suggestive of SDB, Berlin questionnaire, ESS scale, and STOP-Bang questionnaire. Laboratory works up. Pulmonary function tests: to determine FEV1 (% of predicted), FVC (% of predicted) and FEV1/FVC%. Pulse oximeter in sitting position to determine peripheral arterial oxygen saturation (SpO2). Chest X-ray. Full night attended PSG. Among the 75 screened patients, only 57 patients accept to complete the study by doing PSG while remaining patients refused to complete it. We found that among 57 patients who complete the study, the mean age was 38.75 ± 7.69, 24 patients (42.1%) were men and 33 (57.9%) were women. The mean value of BMI was 52.18 ± 10.22 kg/m2; erect awake SpO2 94.89 ± 3.63, Neck circumference 45.19 ± 3. 93 cm and Mallampati score was 2.39 ± 0.86. The score of screening questionnaire of STOP-Bang, Epworth and Berlin questionnaire were 4.58 ± 1.49, 10.14 ± 5.43 and 2.25 ± 0.79 respectively. The prevalence of SDB in studied cases was 84.2%, prevalence of OSAS was 79.2% and the prevalence of OHS was 20.8%. We noticed that obese patients with SDB exhibit statistically significant higher symptoms suggestive of SDB, NC , ESS , STOP-Bang , Berlin questionnaires, PaCO2 and HCO3 values, AHI, ODI, AI, and statistically significant lower SpO2, PaO2 , Sao2, sleep efficiency, minimal SpO2% and REM% in comparison to obese patients without SDB. We also noticed that there was high prevalence of male patients with SDB versus female patients with SDB (100% versus 72.7%) while there were no significant differences as regards age, BMI, Mallampati score, PH, N3%, basal (awake supine) SpO2 and spirometric pulmonary function tests. Our result shown that, there were non-significant differences between OHS and OSAS patients as regard comorbidities in the form of HTN, DM, IHD and dyslipidemia. The overall prevalence of SDB among bariatric populations in Mansoura SDB unit was 84.2%, 79.2% of them were with OSAS and 20.8% were with OHS. There were multiple associated risk factors of SDB among bariatric patients eg. Male sex, prominent symptoms suggestive of SDB (snoring, excessive sleepiness, observed apnea), higher neck circumference, high score of ESS, Berlin and Stop-Bang questionnaires. Screening questionnaires at certain cutoff points has acceptable sensitivity and specificity in prediction of SDB among bariatric populations. Screening questionnaires can be used in classifying the severity of SDB at different cutoff points with acceptable sensitivity and specificity