الفهرس | Only 14 pages are availabe for public view |
Abstract Numerous abnormalities of thyroid hormones in end-stage renal disease (ESRD) have been described, one of these abnormalities is sick euthyroid syndrome.The aim of the study is to assess the frequency of sick euthyroid syndrome in prevalent hemodialysis patients .patients and methods: forty stable prevalent hemodialysis patients were randomly selected from Ain shams university hemodialysis unit and all were subjected to full history and detailed clinical examination especially thyroid gland , CBC , thyroid profile fT3 , fT4 , TSH and rT3 (by ELISA) as well as thyroid ultrasound.Exclusion criteria included patients with known thyroid disorders or receiving drugs affecting thyroid functions.The studied population was divided into 2 groups according to level of fT3 , 27 (67.5%)patients had low fT3 and 13(32.5%) patients had normal level of fT3.there was no statistically significant difference between the 2 groups as regard demographic , laboratory and ultrasound data. The studied population was divided into another 2 groups according to level of rT3.Patients with high level of rT3 had high prevalence of thyroid nodules.Conclusion : there is high prevalence of sick euthyroid syndrome in hemodialysis patients, patients with SES had higher incidence with thyroid nodules which may have prognostic value as nodules may be precancerous.Recommendation: studying risk factors . |