الفهرس 
? Hepatocellular CarcinomaOnly 14 pages are availabe for public view
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Abstract
AFP was significantly higher in HCC group than in cirrhotic and control groups (p<0.001) with median levels (186.5), (9.3), (3.5) ng/ml respectively, and insignificantly higher in cirrhotic group than in control group while CRP level was significantly different among studied groups being highest in HCC group followed by cirrhotic group and lowest in control group (p<0.001) with mean levels (10.5±3.7), (6.1±2.2), (2.4±1.4) mg/dl respectively.
Laboratory results as regard Hb, platelet, albumin, AST, ALT and bilirubin revealed insignificant difference between HCC and cirrhotic group (p > 0.05).
TRX has better diagnostic performance than AFP in differentiating HCC from other groups at a cut off point ≥ 100 ng/ml for TRX where sensitivity and specificity with positive predictive value and negative predictive value (81.8%, 88.9%, 90%, and 80%) respectively and at a cut off point ≥ 25.6 ng/ml for AFP where sensitivity and specificity with positive predictive value and negative predictive value (60%, 76.7%, 72%, and 65.7%) respectively. Combined use of TRX and AFP revealed higher diagnostic performance than using one of each markers alone with sensitivity, specificity, positive predictive value, and negative predictive value (85.4%, 91.3%, 87.8, and 82.4%) respectively.