الفهرس 
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Abstract
Telangiectasias are defined as “a confluence of dilated intradermal
venules of less than 1 mm in caliber”. They originate from similar
mechanisms to varicose veins of larger vessels, whereby turbulent flow leads
to venous hypertension and valvular damage causing reflux and dilatation,
telangiectasias can occur in the absence of larger vessel pathology.
The incidence of telangiectasias has found that the majority of adults will
develop them over the course of a lifetime. 88% of of those affected are women.
Sclerotherapy is a technique used to treat telangiectasias. A liquid or
foam sclerosing agent is injected into the vein with the aim of causing
targeted, localised damage to the endothelium that leads to inflammation,
thrombus formation, Collapse and fibrosis of the vessel. In the absence of
blood flow, the vein loses its red or purple appearance.
The aim of this study is to study the efficacy, safety and complications of
the foam and liquid sclerotherapy with the same agent (polidocanol) and the
same concentration, in comparison to each, in the Treatment of telangiectasias
with respect to visual improvement and resolution including timing of effect,
adverse events, patient satisfaction and quality of life measures.
Twenty five Adult women (50 legs) with clinically diagnosed
telangiectasias of the lower limbs. They were collected from the outpatient
clinic of the Dermatology and Venereology Department and the vascular
surgery unit, Alexandria main University Hospital. Patients were eligible if
presenting for cosmetic reasons for sclerotherapy.
They were randomly divided into two equal treatment groups; the first
group (liquid group) consisted of the right 25 legs subjected to treatment with
Summary
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liquid POL 0.25% while the second group (foam group) consisted of the left
25 legs subjected to treatment with foam POL 0.25%.
In the present study, During sclerotherapy injection, all patients
experienced different degrees of pain except two patients in liquid group and
three patients in foam group , the difference in pain experienced by the
patients in liquid group and foam groups was not statistically significant.
The present study revealed, although erythema was observed in 15
patients (60%) in the foam group and 13patients (52%) in liquid group, there
was no statistically significant difference between both groups.
Similarly, there was no statistically significant difference between
occurrence of urticarial reaction with the use of liquid or foam POL
sclerosants in both groups.
Anaphylactic reaction or systemic allergic reactions were not observed
during the injection of POL in both groups, one patient suffered from dizziness
during foam injection which resolved within few minutes after stoppage of the
intervention, blood pressure was checked for this patient 120/80, with no such
symptom developed with liquid POL in the same patient.
Skin hyperpigmentation was found to be more after injection of foam
POL than after injection of liquid POL after one month follow up ,it shows
improvement in both groups three months after treatment .the difference in
the pigmentation between both groups was statistically non significant at all
follow up visits.
In the present study, the average clinical improvement at time of one and
three months after injection for liquid POL was more than foam POL .the
difference was not statistically significant between both groups.