الفهرس 
Development of Urinary System in Intrauterine Life
Renal Cystic Disease of Genetic Origin:Only 14 pages are availabe for public view
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Abstract
Congenital anomalies of kidney and urinary tract anatomy (CAKUT) are common in children and represent approximately 30%of all prenatally diagnosed malformations. In young children congenital anomalies of kidney and urinary system are leading cause of kidney failure and for kidney transplantation or dialysis. Congenital anomalies occur in various combinations. The presence of one anomaly will indicate search for other anomalies. This study aimed to screened neonates with congenital anomalies in different body organs by ultrasound examination for urological system malformation and evaluated the common
associations between these anomalies and renal anomalies to improve prognosis of urinary system anomalies and delay renal replacement therapy (renal transplantation and dialysis).
The study was done on 40 neonates who had systemic anomalies in different body systems in neonatal center at Tanta
university hospital. Data was collected about gestational age, birth weight,sex,drug intake during pregnancy, diseases associated with pregnancy and family history of similar condition. Through physical examination we searched about systemic congenital anomalies. Neonates who had systemic anomalies were subjected to U/S for renal system to showed associated renal anomalies. In our study percentage of kidney anomalies association was
35% Congenital renal anomalies were detected in 14 patients of the studied patients.The patients with renal anomalies were full term in
11 cases while only 3 patients were preterm. Male to female ratio were 1:1.Neonates with renal anomalies had normal kidney function except 2 cases had ARPKD. They had increase of creatinine and urea level. Most common renal anomalies are MCDK (35.7%), 1ry
megaureter, ARPKD and pelvic kidney (14.29% for each of them),medullary sponge kidney,UPJO and crossed fused kidney (7.14% for each of them).