الفهرس 
Uses of organophosphorus compounds:Only 14 pages are availabe for public view
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Abstract
Acute OP poisoning represents a major health problem. According to the World Health Organization (WHO), one million serious accidental and two million suicidal poisonings with OP occur worldwide every year, and of these, approximately 200000 died, mostly in
developing countries. The problem is compounded by a lack of research evidence regarding diagnosis, grading of severity or management of OP poisoning, despite the large number of OP poisoning cases occurring worldwide
every year. Rapid and effective stabilization and treatment of the poisoned patient has a great role in reducing the number of deaths, improving the short term prognosis of surviving patient and reduceing the number and severity of long term sequelae. Removal of the poison from stomach by gastric lavage (GL) seems to be a practical approach for decontamination. Although highquality evidence showing the benefit of GL in acute poisoning is lacking, it is one of the most commonly used decontamination method for cholinergic insecticide ingestion in developing countries. In contrast, insecticide poisoning with high mortality predominates in developing countries where various decontamination measures may be useful. The aim of this work was to evaluate the outcome of patients with acute organophosphorus poisoning treated with GL in regards to timing
and frequency of the procedure. This study was a randomized clinical trial conducted on 40 patients suffering from acute organophosphorus poisoning admitted to Toxicology Unit, Tanta University Emergency Hospital, between July2015 and January 2016. The main hypothesis was that multiple gastric lavages may improve the outcome in OP poisoned patients. In this study, 40 patients of both sexes with acute OP poisoning divided equally into 2 groups, 20 patients for each group. group I (received standard therapy plus single gastric lavage procedure) and group II (received standard therapy plus
multiple gastric lavage procedures “at admission,4 hrs and 8 hours after first lavage