الفهرس | Only 14 pages are availabe for public view |
Abstract CA-125 is defined first as a tumor marker specially with ovarian cancer.Recently elevated serum levels of CA-125 are found in physiological conditions as menstruation and pregnancy and in pathological conditions as endometriosis, fibroid, pelvic inflammatory disease, ovarian hyperstimulation syndrome, end-stage liver disease and a variety of gynecological and non-gynecological neoplasms. In pregnancy, serum CA-125 levels are increased in early pregnancy and immediately after birth implicating the disintegration of the maternal decidua (i.e., blastocyst implantation and placental separation) as a possible source of the tumor marker elevation. This study was conducted at Ain Shams University Maternity Hospital to assess free serum CA-125in pregnant women with preeclampsia in the third trimester to find out possible relation between the level of CA-125and severity of preeclampsia. |