الفهرس 
AbstractOnly 14 pages are availabe for public view
 |  | from | 151 |  |  |
| | | from | 151 | | |
Abstract
Targeted Drug Delivery To Specific Tissue Or Cells Drastically Reduces The Severity Of Unwanted Side Effects. The Use Of Transferosomes In Drug Targeting Is Considered As One Of The Most Promising Techniques In This Field. The Aim Of This Work Is To Prepare Stable Vesicles Encapsulating The Non-Steroidal Anti-Inflammatory Drug, Lornoxicam, Which Will Eventually Be Formulated In A Gel As A Final Dosage Form. The Prepared Gel Is Intended To Be Used In Treatment Of Severe Inflammations.
Accordingly, The Work In This Thesis Is Divided Into Two Chapters:
Chapter (1)
Enhancement Of Lornoxicam Solubility By Inclusion Complexation With Cyclodextrin
This Chapter Deals With The Preparation Of Inclusion Complexes Of Lornoxicam With Β-Cyclodextrin And 2-Hydroxypropyl-Β-Cyclodextrin In Different Ratios Through Physical Mixing And Freeze-Drying. The Prepared Mixtures Were Then characterized Through X-Ray, DSC, NMR, IR And Release. The Results Showed That 2-Hydroxypropyl-Β-Cyclodextrin In Ratio 1:2 Give (Lornoxicam: Polymer) The Most Soluble Complex Formed By Freeze-Drying.