الفهرس 
Vascular Access of HemodialysisOnly 14 pages are availabe for public view
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Abstract
Background. Thrombosis of the central venous haemodialysis catheter compromises dialysis adequacy and catheter survival. Heparin containing catheter-locking solution has been associated with bleeding, interferes with INR (prothrombin time/international normalized ratio) measurements and is costly. Sodium citrate has been used successfully as a catheter-locking solution.
Haemodialysis catheters used for vascular access are frequently complicated by infection and catheter‐related thrombosis. Improvement of interdialytic locking solutions could reduce these problems. Trisodium citrate (TSC) has been advocated in recent years because it might have antimicrobial qualities.
Method. In our study , comparison between sodium citrate and heparin as locking solution , each group contains 105 patients, comparison between both groups accordingly to frequency dialysis catheter thrombosis, dysfunction, blood stream associated infection, and catheter site infection for a period of 3 weeks of dialysis catheter insertion.
Results. Increase frequency of thrombosis among sodium citrate group, on the other hand increase frequency of blood stream associated infection with heparin groups but with no statistically significance.
Conclusion. Our study demonstrate that Sodium is a unique alternative to heparin as locking solution for temporary dialysis catheters, by its antiseptic and antithrombotic effect.