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العنوان
Preparation, Spectroscopic characterization of metal complexes of Diacetyl Schiff-base and study Therapeutic effect as anti hepatocellular carcinoma /
المؤلف
El-Mahsarawy, Alzahraa Ibrahim Mohammed.
هيئة الاعداد
باحث / الس رٍاء ابرا هٍ? محند المعصرا ىّ
مشرف / عبده سعد الطبل
مشرف / مشيرة محمد عبد الواحد
مشرف / رجاء الشيخ شهيب عبد الناصر
الموضوع
hepatocellular carcinoma - prevention & control.
تاريخ النشر
2017.
عدد الصفحات
ill. ;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Inorganic Chemistry
تاريخ الإجازة
5/2/2017
مكان الإجازة
جامعة المنوفية - كلية العلوم - الكيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

Mn(II), Fe(II), Co(II), Ni(II) , Cu(II), Zn(II), Pb(II), Sr(II), Cd(II), Mg(II) and Ag(I) complexes of ligand(1) have been prepared and characterized by element analysis, IR, UV-Vis spectra, magnetic moment, conductances, 1H-NMR spectraand mass spectra, Thermal analysis (DTA and TGA) and ESR measurments. The analytical and IR data show that, the ligand behaves as neutral tetradentate or dibasic tetradentate. Molar conductances in DMF indicate that, the complexes are non-electrolytes. ESRspectra of solid Cu (II) complexes at room temperature show axial type (dx2-y2 ) with covalent bond character in an octahedral environment. Some complexes showed inhibitory activity agtainst hepatocellular carcinoma (HepG-2 cell line) compared with a standard drug (sorafenib)