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Abstract Transcranial ultrasound is a primary imaging modilaty imployed in the assessment of neonatal and infant brain, improvements in critical care medicine have resulted in increased survival of premature,low birth weight and asphyxiated infants.Several problems are associated with imaging of critically ill neonates,These include the choice of imaging technique,the timing of imaging study and the transporting of acutely ill neonates,many of whom require ventilatory assistance and multiple indwelling catheters . Sonography is the neuro-imaging technique that is well established in its use in the neonatal nursery.It is the accepted initial investigation for the diagnosis of germinal matrix, intraventricular haemorrahge,or both in the premature infants.Hydrocephalous complicating intraventricular haemorrhage can be readily diagnosed and monitored,Also sonography used to diagnose congenital intracranial anomalies. The present study aimed at detecting cranial ultrasonographic abnormalities in preterm neonates (30-34weeks) under the effect of different risk factors, with finding the relation between these ultrasonographic abnormalities and the presenting clinical data. This research was conducted on 120 preterm neonates, whom were admitted at NICU of Benha children hospital, they were 67 males (55.8%) & 53 females (44.2%). Their gestational age ranged from 30 to 34 weeks with a mean of 32.6±1.3weeks . Detailed history taking,full clinical examination and laboratory investigation were performed before carrying out cranial ultrasonographic scanning for all neonates at 7-14 days and the follow up cianial ultrasounds was done after one month of the first one for follow up ,there were106 cases with normal ultrasonography ,while the remaining 14 cases having different cranial abnormalities on cranial ultrasound , this abnormalities including IVH , HIE , congenital hydrocephalus and PVL . Our results proved that all infants greater than 30 weeks gestation with significant abnormalities on cranial US had specific perinatal risk factors (eg; ante-partum hemorrhage, PROM, traumatic delivery,…) or clinical findings(eg; poor reflexes, pallor, cyanosis, convulsions and apnea) that would have indicated the need for prompt cranial U/S evaluation. Also there is Significant relationships were detected between follow up ultrasound and the first CUS findings . Our study supports the recommendation by the American Academy of Neurology and the Child Neurology Society that routine screening cranial ultrasounds can be limited but suggests that the gestational age cut off should be 30 weeks or more. In conclution, cranial ultrasonography has been a major advance in the study of neonatal brain,it is protable,safe,non invasive ,low cost and highly effective technique that is of considerable value in evaluation of neonatal intracranial disorders and should be included within integrated approach to CNS imaging in the neonates. |