الفهرس | Only 14 pages are availabe for public view |
Abstract Diabetic macular edema is one of the leading causes of visual impairment in diabetic patients. Fluorescein angiography is an imaging modality that has been used to identify areas of vascular leakage, and it is a kind of qualitative and functional study. Optical coherence tomography is an imaging technique that produces high-resolution cross-sectional images of the retina, and it offers a structural and quantitative analysis of clinically significant diabetic macular edema. Optical coherence tomography is more sensitive to small changes in retinal thickness than slit-lamp biomicroscopy. This is study was done over 100 eye of 66 patient, 43 of them (65.5%) were males with mean age (62.2 ± 7.62), Ranged from 44.0-83.0 years. All patents were suffering from type 2 diabetes mellitus with Mean duration of diabetes mellitus (16.03±6.58), ranged from 9.0-32.0 years. The mean pretreatment central macular thickness for the whole group measured by OCT was (439.96± 178.51), ranged from 180.0-890.0 and the mean visual acuity pretreatment was (0.24± 0.15), Ranged from 0.05-0.66. Our results showed statistically significant negative correlation between the pre treatment central macular thickness and the visual acuity (r= - 0.65, p value <0.001). Also, there was statistically significant Positive correlation between the pre treatment central macular thickness and the duration of diabetes mellitus (r=0.55, p value <0.01) In this study the mean Post-treatment central macular thickness measured by OCT was (316.89 ± 140.10), ranged from 140.0-680.0 and the mean visual acuity Post-treatment was (0.41± 0.24), Ranged from 0.10 to 1.00. There was statistically significant negative correlation between the Post treatment central macular thickness and the post treatment visual acuity (r=-0.55, p value <0.001). However, statistically significant Positive correlation was found between the post-treatment central macular thickness and the duration of diabetes mellitus (r=0.56, p value <0.001) In summary, our study revealed a significant correlation between the features of OCT and fluorescein angiography and visual acuity in diabetic macular edema. The analysis of clinically significant macular edema based on both OCT and fluorescein angiography can provide information that may be Useful to disclose the pathogenesis of the edema and to optimize the treatment for each type. |