Search In this Thesis
   Search In this Thesis  
العنوان
Predicting visual outcomes for Diabetic macular edema using optical coherence tomography and fluorescein angiography /
المؤلف
El Gohary, Ahmed Mohamed Mahmoud.
هيئة الاعداد
باحث / احمد محمد محمود الجوهري
مشرف / صابر حامد السيد
مشرف / اسامة عبد الله المرسي
مناقش / صابر حامد السيد
الموضوع
Tomography, optical coherence - congress.
تاريخ النشر
2017.
عدد الصفحات
143 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب العيون
تاريخ الإجازة
15/1/2017
مكان الإجازة
جامعة المنوفية - كلية الطب - طب وجراحة العين
الفهرس
Only 14 pages are availabe for public view

from 143

from 143

Abstract

Diabetic macular edema is one of the leading causes of visual impairment
in diabetic patients.
Fluorescein angiography is an imaging modality that has been used to
identify areas of vascular leakage, and it is a kind of qualitative and functional
study. Optical coherence tomography is an imaging technique that produces
high-resolution cross-sectional images of the retina, and it offers a structural and
quantitative analysis of clinically significant diabetic macular edema. Optical
coherence tomography is more sensitive to small changes in retinal thickness
than slit-lamp biomicroscopy.
This is study was done over 100 eye of 66 patient, 43 of them (65.5%)
were males with mean age (62.2 ± 7.62), Ranged from 44.0-83.0 years.
All patents were suffering from type 2 diabetes mellitus with Mean
duration of diabetes mellitus (16.03±6.58), ranged from 9.0-32.0 years. The
mean pretreatment central macular thickness for the whole group measured by
OCT was (439.96± 178.51), ranged from 180.0-890.0 and the mean visual
acuity pretreatment was (0.24± 0.15), Ranged from 0.05-0.66.
Our results showed statistically significant negative correlation between
the pre treatment central macular thickness and the visual acuity (r= - 0.65, p
value <0.001). Also, there was statistically significant Positive correlation
between the pre treatment central macular thickness and the duration of diabetes
mellitus (r=0.55, p value <0.01)
In this study the mean Post-treatment central macular thickness measured
by OCT was (316.89 ± 140.10), ranged from 140.0-680.0 and the mean visual
acuity Post-treatment was (0.41± 0.24), Ranged from 0.10 to 1.00. There was
statistically significant negative correlation between the Post treatment central
macular thickness and the post treatment visual acuity (r=-0.55, p value
<0.001). However, statistically significant Positive correlation was found
between the post-treatment central macular thickness and the duration of
diabetes mellitus (r=0.56, p value <0.001)
In summary, our study revealed a significant correlation between the
features of OCT and fluorescein angiography and visual acuity in diabetic
macular edema. The analysis of clinically significant macular edema based on
both OCT and fluorescein angiography can provide information that may be
Useful to disclose the pathogenesis of the edema and to optimize the
treatment for each type.