الفهرس 
Gross AnatomyOnly 14 pages are availabe for public view
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Abstract
With introduction of molecularly targeted chemotherapeutics, there are increasing needs for defining new response criteria for therapeutic success; because use of morphologic imaging alone may not fully assess tumor response.. Computed tomographic perfusion (CTP) imaging of the liver provides functional information about the microcirculation of the normal parenchyma and focal liver lesions as well and is a promising technique for assessing the efficacy of various anticancer treatments .
CT-perfusion also shows promising results for diagnosing hepatocellular carcinoma or metastatic tumors, for predicting early response to anticancer treatments , and for monitoring tumor recurrence after therapy..
Many of limitations of early CT-perfusion studies performed in the liver , such as: limited coverage, motion artifacts, and high radiation dose of CT are being addressed by recent technical advances. These include a wide area detector with or without volumetric spiral or shuttle modes, motion correction algorithms and new CT reconstruction technologies such as iterative algorithms .
Although several issues related to perfusion imaging—such as paucity of large multicenter trials, limited accessibility of perfusion software and lack of standardization in methods—remain unsolved, CT-perfusion has now reached technical maturity, allowing for its use in assessing tumor vascularity in larger-scale prospective clinical trials.