الفهرس 
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Abstract
Background: The lack of vitamin D during pregnancy may result in poor fetal growth and altered neonatal development that may persist into later life. Recognition of risk factors and early detection of vitamin D deficiency during pregnancy is important in order to prevent neonatal vitamin D deficiency and related complications.
Objective: The aim of the current study is assessment of 25-hydroxyvitamin D status in cord blood among newborns and its correlation with maternal risk factors.
Method: This is an analytic cross sectional study which was performed in Fayoum governorate. The study enrolled 90 pregnant women and their newborns. All mothers were assessed for careful history taking about; age, parity, dietary habits, life style, vitamin D supplements, hours of sun exposure per day, clothing style and history of pre-eclampsia, gestational diabetes or any other disease. Also assessed clinically for body mass index (BMI) and skin color. Anthropometric measurements including weight, length, and head circumference were performed to their neonates and cord blood samples were collected and evaluated for 25-OH vitamin D level.
Results: Mean of 25-OH vitamin D level in cord blood among study group was (54.1±27.7) ng/ml, 23.3% were vitamin D insufficient, 73.3% were sufficient and 3.4% showed vitamin D intoxication. Newborns of non- obese mother showed significant higher vitamin D level in cord blood when compared to newborns of obese mothers (P<0.0001), newborns of non-diabetic mother showed higher vitamin D level when compared to newborns of diabetic mother (P=0.001), also newborns of mothers with white skin color showed vitamin D level higher than newborns of mothers with dark skin color (P<0.050). There was a significant correlation between sun exposure, vitamin D supplementation during pregnancy and middle socio-economic state and state of vitamin D level in cord blood(P<0.05).
Conclusion: Prevalence of vitamin D deficiency was more among newborns of obese, diabetic and dark skin mothers; also prevalence of vitamin D deficiency was more among neonates born to mothers with middle socio- economic state, inadequate sun exposure and inadequate vitamin D supplementation during pregnancy.
Key words: Vitamin D, Pregnancy, Neonates.