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Abstract The Most hospital-acquired infections are transmitted by health care personnel who fail to practice proper hand hygiene or who fail to change gloves between client contacts. Infection control is an issue wherever the client may be found, not just in the acute hospital. Aim of the study: The study aimed to evaluate the effectiveness of planned health education program on nurses’ knowledge and practice for preventing infection in gastrointestinal endoscopy units at major hospitals in Yemen. Methods: The Quasi-experimental (One group pre-test and post-test design) research design was used in this study. Purposive sample included all available (46) nurses. Tools used for data collection included self-administered questionnaire, an observation checklist. Results: The mean age of the nurses were 30.087± 4.74143 years, about two thirds were female and 58.7% had diploma degree. The most obstacle to implementation infection control was inadequate resources 69.6%. There was significant improvement in total scores and all items of knowledge and practice regarding infection prevention and control measures before and after applying health education program. After implementation of health education program, the nurses had 78.3% adequate knowledge and 67.4% good practice. Conclusion: Planned health education program was effective in improving nurses knowledge and practice of nurses regarding infection prevention and control measures and endoscopy reprocessing at endoscopy units. Recommendations: Continuous educational and training is for all health team members in endoscopy units about infection prevention and control. |