الفهرس 
Introduction
Chapter I: Macromorphology of Melissa officinalis L.Only 14 pages are availabe for public view
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Abstract
Melissa officinalis L. is a perennial herb belongs to family Lamiaceae, native to the Mediterranean region and southern Europe. It is commonly named as ‘lemon balm’ because of its lemon-like flavor and fragrance. This work consists of three parts:
Part I: Botanical study of Melissa officinalis L. which include the macro-and micromorphology of the leaf, stem and root in both entire and powdered form.
Part II: Phytochemical study of Melissa officinalis L. including phytochemical screening, extraction, fractionation, isolation and identification of the different constituents from leaves and stems of Melissa officinalis L. in addition to the investigation of the saponifiable matter (fatty acids) and the unsaponifiable matter of Melissa officinalis L.
Part III: Biological study of Melissa officinalis L. such as analgesic activity, anti-inflammatory activity, antipyretic activity, in vitro antioxidant activity and antimicrobial activity. Melissa officinalis L. is a perennial herb or shrub, 0.25-1 m in height. The stems carry simple, green and hairy leaves. Botanically:The leaves are simple, cordate to lanceolate, opposite decussate, exstipulate, petiolated and with a symmetric base. The petiole is cylindrical, hairy and green in colour. The stem is quadrangular, erect, green in colour with monopodial branching. The upper part is herbaceous and hairy, whereas the lower part is harder and tough (suffruticose). The root is represented by a cylindrical dark brown tap root carrying several lateral rootlets. The root is odourless and has a bitter taste.The epidermis is formed of one row of rectangular cells covered with a thin smooth cuticle. The cells are polygonal, isodiametric to slightly elongated with straight anticlinal walls showing anomocytic stomata. Both glandular and non-glandular trichomes are present. The mesophyll is dorsiventral, differentiated into a discontinuous upper palisade layer and spongy tissue. The spongy tissue is formed of 3-5 rows of thin-walled rounded or slightly irregular collenchyma with wide intercellular spaces. Chemically: Preliminary phytochemical screening revealed the presence of carbohydrates, triterpenes, saponins, tannins, flavonoids and coumarins, in addition to absence of crystalline sublimates, cardiac glycosides and anthraquinone glycosides. The air dried powdered leaves and stems (2 kg) of Melissa officinalis L. were fractioned and subjected to extensive column chromatographic separation and purification steps leading to isolation of compounds 1-10 which identified as: 23-sulfate ester of 2α, 3β, 19α, 23-tetrahydroxy-urs-12-en-28oic acid 28-O-β- glucopyranoside, 3,23-disulfate ester of 2α,3β, 19α,23-tetra-hydroxyurs-12-en-28-oic acid 28-O-β-gluco-pyranoside, Melissin-I, 4-Hydroxy coumarin, Melissin-II and Melissin-III. Finally, Biological study of Melissa officinalis L. including analgesic activity, anti-inflammatory activity, antipyretic activity, in vitro antioxidant activity and antimicrobial activity.