الفهرس 
Postoperative painOnly 14 pages are availabe for public view
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Abstract
Lumbar disc surgery is associated with considerable postoperative pain. Although these procedures may be performed using microsurgery techniques, patients suffer from postoperative pain after the procedure, which delays their return to normal activities, the management of postoperative pain plays an important role in neurological recovery. Different modalities and drugs for pain management following laminectomy have evolved over time. This includes intravenous, intramuscular, epidural, spinal, instillation and infiltration routes of analgesia. Addition of adjuvants like magnesium and tramadol has shown promising results. A wound infiltration is a method of postoperative analgesia commonly used alone or with other analgesic regimens. It was developed to improve postoperative analgesia, reduce opioid consumption and hasten patient recovery. The use of local anesthetics (LAs) instead of opioid minimizes opioid adverse reactions, decreases resting pain, pain on motion, and thus allows better patient mobility. Magnesium is widely used in perioperative settings and has shown to decrease the anesthesia and analgesia requirements effectively. Magnesium is a physiological blocker of the N-methyl D-aspartate (NMDA) receptor. Post-synaptic depolarization following nociceptive inputs decreases this ability to block calcium inflow through the receptor. Thus, by blocking the NMDA receptor throughout the perioperative period, magnesium might play a key role in postoperative pain, sensitization process and hyperalgesia.