الفهرس 
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Abstract
In ICSI cycles controlled ovarian hyperstimulation is an important parameter of the success rates.
This study was carried out on 200 patients complaining of infertility and undergoing antagonist ICSI Cycles. They were divided into two groups each group contains 100 patients, group A 150-225 IU HMG starting on day 2, group B received 150-225 IU HMG starting on day 3, both groups received luteal support (progesterone supplementation).
Polycystic ovaries was an exclusion criteria also Women with history of malignancy were considered ineligible for medical reason.
Serial ultrasound scans to assess the follicular growth were done, the clinical pregnancy was the main assessment parameter.
No immediate complication from the drug use took place, no late complication was recorded.
The results of the current analysis in a GnRH antagonist regimen indicate that, on a group level, initiation of controlled hyperstimulation on day 2 versus day 3 regarding l the final E2 in group I ranged from 1100 to 4730 mIU/ml with a mean value of 2851.6 ± 612.3 mIU/ml, while in group II it ranged from 705 to 4390 mIU/ml with a mean value 2733 ± 526.5 mIU/ml. Using independent sample t test, there was no significant difference between the two studied groups (t=1.133, p=0.213).
Regarding P4 on final maturation day in group I ranged from 0.64 to 1.92 with a mean value of 0.928 ± 0.307, while in group II it ranged from 0.71 to 2.00 with a mean value 0.99 ± 0.452. Using independent sample t test, there was no significant difference between the two studied groups (t=1.23, p=0.11).
Regarding the total number of gonadotropin ampoules used in group I ranged from 21 to 40 with a mean value of 30.11 ± 6.85, while in the group II it ranged from 23.0 to 42.0 with a mean value 33.58 ± 8.41. Using independent sample t test, there was no significant difference between the two studied groups (t=0.958, p=0.398).
Regarding the number of antagonist ampoules used in group I ranged from 3 to 4 with a mean value of 2.71 ± 2.71, while in the group II it ranged from 3.0 to 5.0 with a mean value 2.75 ± 0.311. Using independent sample t test, there was no significant difference between the two studied groups (t=0.871, p=0.338).
Regarding the endometrial thickness in group I ranged from 7 to 10 mm with a mean value of 8.93 ± 1.074 mm, while in the group II it ranged from 7.2 to 10 mm with a mean value 7.98 ± 2.01 mm. Using independent sample t test, there was no significant difference in endometrial thickness between the two studied groups (t=1.014, p=0.162).
Regarding the Number of days of stimulation in group I ranged from 8 to 10 with a mean value of 9.17 ± 0.91, while in the group II it ranged from 8.0 to 11 with a mean value 9.63 ± 0.78. Using independent sample t test, there was no significant difference in Number of days of stimulation between the two studied groups (t=1.33, p=0.121).
Regarding the number of M II oocytes in group I ranged from 3 to 19 with a mean value of 12.1 ± 3.98, while in the group II it ranged from 3.0 to 20 with a mean value 12.91 ± 12.91. Using independent sample t test, there was no significant difference in Number of M II oocytes between the two studied groups (t=1.006, p=0.108).
Regarding the Fertilization rates in group I ranged from 3 to 10 with a mean value of 8.33 ± 2.18, while in the group II it ranged from 4.0 to 14 with a mean value 9.21 ± 3.62. Using independent sample t test, there was no significant difference in Fertilization rates between the two studied groups (t=0.78, p=0.428).
Regarding embryo quality, showed embryos grade A; group 1420 embryo (56%) vs 550 embryos (64%) in group 2.
Embryos grade B; 274 embryos (36.5%) in group 1 vs 260 embryos (30.2%) in group 2.
Embryos grade C; 56 embryos (7.5%) in group 1 vs 50 embryos s(5.8%) in group 2.
While regarding clinical pregnancy rate, showed that in group I there were 66% patients got pregnant and 34% did not get pregnant, while in group II, there were 69% who got pregnant and 31% whom did not get pregnant. Using Pearson Chi-Square there was no significant difference between the two groups regarding pregnancy (X2=0.85, p=0.215).