الفهرس 
MYELODYSPLASTIC SYNDROMEOnly 14 pages are availabe for public view
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Abstract
Background: Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic disorders characterized by bone marrow failure, dysplasia, and an increased likelihood of evolution to acute myeloid leukemia (AML). Copper deficiency can be a very important treatable cause of a picture resembling MDS. A lot of cases have been reported through the years since the first case in 1994. Anemia and neutropenia caused by copper deficiency can be completely reversed by copper supplementation.
Result: Of 50 MDS patients included in the study,4 patients were diagnosed with copper deficiency. Low serum copper correlated with anemia (r= 0.424, P= 0.002) and low WBCs count (r=0.424, P= 0.030) and inversely strongly correlated with thrombocytopenia (r= - 0.595, P <0.001). A strong statistical correlation was also found between low serum copper and ceruloplasmin level (P=0.001).
Conclusion: copper deficiency should be kept in mind as a treatable reversible important differential diagnosis of myelodysplastic syndrome.