![]() | Only 14 pages are availabe for public view |
Abstract A total number of 140 male albino rats were divided into 7 groups each group included 20 rats: Control group, two monosodium glutamate (MSG) treated groups (group received MSG orally in the chemical form & group fed on processed cheese as natural source ofMSG), two Vit C & Vit E treated groups (group received vit C & vit E in the chemical form & group fed on orange juice & cotton seed oil as natural source of each vitamin respectively and two MSG, vit C & vit E treated groups one group received them in chemical form & other group fed on natural sources containing them). All groups were fedd for 4 weeks and used to investigate the monosodium glutamate administration deleterious effects on male rat reproductive system and to examine the role of some antioxidants namely vit. E & C in minimizing such hazards. They all subjected to determination of serum thiobarbituric acid reactive substance (MDA), serum superoxide dismutase (SOD) enzyme activity, serum testosterone level and histological examination of testicular tissues. According to the study results, the deleterious effects of MSG were minimized by administration of vit E & C more effectively in the chemical fonn than from natural sources. So it is recommended to use vi.t. E & vit C. tablets routinely as protective measure against deleterious effects of MSG. |