الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Preeclampsia was formerly defined as a multisystem disorder characterized by new onset of hypertension systolic blood pressure (SBP) ≥ 140 mmHg and/or diastolic blood pressure (DBP) ≥ 90 mmHg) and proteinuria (> 300 mg/24 h) arising after 20 weeks of gestation in a previously normotensive woman. Aim: Aim of this to study the association between the quantitative assessment of immature platelet fragments (%-IPF), immature platelet count (A-IPC) and diagnosis of HELLP syndrome. Subjects: The study population will include 3 groups. group 1: This include 28 patients who are pregnant more than 28 weeks and initially diagnosis as HELLP syndrome before taken any treatment. group 2: This include 28 patients are pregnant more than 28 weeks and initially diagnosis as sever preeclampsia. group 3: this will include women who are pregnant more than 28 weeks. Results: The current study showed significant negative correlation between platelet count and IPF, and a significant positive correlation between platelet count and A-IPC in included women of the three groups. But regarding to serum creatinine, the median serum creatinine was significantly higher in women of group with help syndrome when compared to those of group II and group III. Conclusion: There is a positive correlation between platelet count and A-IPC in patient initially diagnosed HELLP syndrome comparing to anther women diagnosed as severe preeclampsia and normal healthy pregnant women and also there is negative correlation between platelet count and IPF of the same comparing groups. |