الفهرس 
Fatigue in Different Neurological Conditions
Pharmacological TreatmentOnly 14 pages are availabe for public view
 |  | from | 158 |  |  |
| | | from | 158 | | |
Abstract
Background and Purpose:
Stroke is a major cause of hospital admission and long term adverse consequences globally and post-stroke fatigue ( PSF ) is considered a major adverse consequences due to its wide prevalence, persistence and its adverse effect on the patients’ quality of life following stroke.
This study examined the prevalence and possible determinants of PSF in a sample of Egyptian patients with ischemic stroke and its effect on their health related quality of life ( HRQL ).
Methods:
Fifty Egyptian patient with ischemic stroke were recruited from neurology departments and stroke units at Ain Shams University Hospitals.
Patients’ medical history, general and neurological examination, stroke severity at admission using NIHSS, lesion location using MRI brain with diffusion, C-Reactive Protein and lipid profile were assessed at admission the the patients were followed for functional disability using MRS, post-stroke anxiety and depression using HADS and PSF using FSS at one month and three months of the onset of symptoms and its impact on the patients’ post-stroke HRQL using SSQOL scale.
Results:
Mean age of the stroke survivors was 57.14 years (SD 11.65 years). The majority were males ( 58.0% ). After controlling demographic and stroke related variables, PSF was found in high prevalence rate among the examined sample ( 96.0% ) and was linked to stroke severity at admission, lesions in the posterior circulation territory and post-stroke anxiety and depression. Also PSF was highly linked to post-stroke HRQL and affect all its domains.
Conclusion:
PSF is a major debilitating adverse consequence among stroke survivors with wide prevalence and has several possible determinants due to the complexity of symptoms. Identifying these determinants is of much importance to provide better understanding, early prediction and appropriate interventions which may assist in enhancing HRQL of stroke survivors.