الفهرس 
Liver Resection for HCCOnly 14 pages are availabe for public view
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Abstract
Background: Hepatocellular carcinoma (HCC) is an increasingly prevalent clinical problem worldwide and is the third most common cause of cancer-related deaths and in Egypt it ranks 2nd and 6th most common cancer among men and women. HCC has a rising incidence in Egypt mostly due to high prevalence of viral hepatitis and its complication.
Aim of the Work: This thesis aims to compare liver resection versus Living Donor liver transplantation in the management of early HCC.
Patients and Methods
Methodology: This study is a cohort prospective analysis of 40 patients underwent surgical intervention for HCC, 20 of them underwent LDLT and the other 20 patients underwent liver resection and have been followed up for the outcomes and complications that may occur. This study was done in Ain Shams University Hospitals and EL Sahel Hospital. Ethical approval from Ain Shams University Hospitals’ ethics committee was obtained.
Results: This study compare between 20 cases of early stage HCC which underwent transplantation and 20 cases of same disease underwent liver resection, of those underwent transplantation 4 cases were excluded due to incomplete follow up and missed data.
Discussion: In our study, there is no significant difference between both groups regarding patient ages. In our study, as regard the demographic data (pre-operative variables): age, AFP, CHILD and MELD were comparable between both groups and the patients with high MELD score more than 15 or CHILD B&C were excluded.
Conclusion: Although most literatures agree that recurrence following resection is more common than following LT with, sometimes, less survival rates following LT, we didn’t find significant difference in our short-term follow up study between both groups in either recurrence or survival. Moreover, there was no difference in overall complication rate between both groups.