الفهرس 
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Abstract
Background : Tramadol is a widely used synthetic centrally acting opioid analgesic for the treatment of moderate to severe pain. Although Tramadol was generally considered to be devoid of any serious adverse effects of traditional opioid receptor agonists, such as respiratory depression and drug dependence. Many Egyptians die because of a road traffic accident every year. The main reasons of traffic road accident are lack of awareness about traffic sense codes and orders and driver related factors. Aim of the study: This research investigates the correlation between Tramadol blood level & severity of trauma among drivers. In addition, to clarify problems that need to be addressed then put recommendations that can reduce the percentage of life threatening conditions linked to Tramadol abuse.
Patients and Methods : Based on the investigated disorder, the study design was a cross sectional study was conducted among driver patients who were transported to Mansoura University Emergency Hospital (MUEH) in motor car accident in the period from the 1st of January to 31st of December 2014. An approval from Mansoura University Ethical Committee was taken and an informed consent was obtained from all cases. The studied patients were divided into 2 Groups. group 1: Drivers came in motor car accidents and show Positive tramadol level. (n=46) group 2: Drivers came in motor car accidents and show negative tramadol level. (n=24). Results and Conclusion:
Increase in tramadol consumption – related accidents among young adults.
• The severity of trauma rises with presence of tramadol but not significantly correlates with the changes in tramadol levels. There is correlation between the severity of trauma after RTCs with plasma tramadol level. Human factors eg, lack of awareness about traffic sense codes and orders account for the majority of RTCs causes.