الفهرس 
Oral administration of L-amino acidsOnly 14 pages are availabe for public view
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Abstract
Physicians prescribe certain types of amino acids in a medication form for some patients to treat several pathological cases such as treatment of depression, improvement of immune system performance, acceleration of wound healing process and cell regeneration, to help some hormones (e.g. growth hormone) to perform their functions, treatment of allergies and autoimmune diseases, and remediation of some liver and kidney diseases. In this connection a number of researches revealed the efficiency of certain amino acids to treat several pathological cases and improvement of human health.
On the other hand, a lot of people have amino acids in a mixture form by oral and/or intramuscular injection routes as food supplements for body building and increasing of muscle mass as in case of athletes. In addition to some amino acids were taken as artificial sweetners for diet and obesity patients. In this connection previous researches exhibited some adverse effects owing to administration of amino acids in a mixture form for athletes and feeding of some amino acids as artificial sweetners (e.g. aspartame) for diet and obesity patients.
Accordingly, the present study was carried out to determine (i) the adverse effects occurring with administration of amino acids for experimental rats (ii) the cause of these adverse effects, which may be due to the following parameters:
• Administration of amino acids in overdose.
• Administration of amino acids via oral or injection routes.
• Administration of amino acids in the DL- or L- forms.
• Administration of certain amino acids (e.g. BCAA).Therefore, these different parameters were investigated in this work via experimental rats which were divided into 7 groups and each group consists of 5 rats. The amino acid mixtures were administered for rats by intramuscular injection or oral feeding via stomach syringe. group (1) was fed only on the basal diet and served as the control group. The other groups received the different types of amino acid mixtures besides feeding on the basal diet. Orally by stomach syringe, groups (2, 4 & 6) received mixtures of DL-BCAA, L-amino acids and DL-amino acids, separately. By intramuscular injection, another groups (3, 5 & 7) received mixtures of DL-BCAA, L-amino acids and DL-amino acids, separately. These groups received the different types of amino acid mixtures daily for 30 days at a dose of 100 mg/kg body weight.