الفهرس 
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Abstract
SAMMARY
• The effect of 4 some colloids of vegetable and animal origins (sodium alginate ,propolis,carob seeds powder ,carob seeds extract ,Arabic gum and their formulation) was studied to cope with hypercholesterolemia using male albino rats . To obtain the hypocholesterolemia rats induction,rats fed on high fat diet plus cholesterol. Hypercholesterolemic rats fed on individual colloids and their collection at 5 or 7.5%levels,for 42 days .Biological and biochemical parameters revealed the following.
• Hypercholesterolemia raised the BWG and FI, while lowered the FER. Colloids treatments reversed these change,provided that maximum improvement recorded for the carob powder diet.
• Liver, hearts,spleen,kidneysand pancreas relative weights increased by hypercholesterolemia,while reduced due to feeding with colloids diet,The colloid lowest.
• Weights (ROW) among differenttreatments was found for carob powder diet. Relative organs
• Serum glucose was raised due to hypercholesterolemia , while decreased appreciably compared to control (+)group when inflicted rats received the colloids specially the carob powder.
• Hypercholesterolemia raised the levels of serum TC and TG, which were reduced when afflicted rats fed on diets containing the different colloids and their mix, in particular that of the carob powder. The results indicated no synergistic action for the different individual colloids.
• Due to hypercholesterolemia VLDL & LDL increased while the HDL decrease .this was reversed when inflicted rats fed on diets containing the colloids,particularly that of the carob powder group, which revealed maximum decrease of VLDL &LDL, and maximum increase of HDL.
• The total summation of lipids profile change exhibited in the AI value(VLDL+LDL/HDL). It was found that hypercholesterolemia raisedtheAI value appreciably, while considerable reductions accusedwhen afflicted rats fed on diets containing the colloids,in particular that of the carob powder treatment.
• Hypercholesterolemia lowered significantly the T.P in serum , which was raised when inflicted rats fed on colloids diets that contained the carob powder.
• Due to hypercholesterolemia T. BiL .increased appreciable .when the afflicted rats fed on colloids diets T.BiLdecreased, in particular for that fed on the carob powder.
• Hypercholesterolemia increased the infiltration of AST ,ALT & ALP enzymesform liver,leading to their increase in the serum. Thisaccompanied by the rise of AST/ALT ratio. The reverse, however, recorded whenrats fed on diets containing the colloids, indicating correction of liver function disorders.
• Du to hypercholesterolemia serum MDA was significantly raised,which wasreduced when the inflicted rats fed on colloids diets .Minimum MDA recorded for the carob seedsdiet.
• GSH reduced considerably by hypercholesterolemia ,while the reverse was found when afflicted rats fed on colloids , in particular that of the carob powder diet .
• Catalase activity (CAT) in serum significantly reduced due to hypercholesterolemia indicating less in the antioxidants .never the less when inflicted rats fed on the colloids diets , especially that of sodium alginate and carob seeds groups CAT considerably increased with non-significant difference between them .
• Hypercholesterolemia caused considerable loss of GPXactivity, which was raisedwhen rats fed on diets containing colloids ,in particular that of the carob seeds treatment .
• Histopatological structure of internal organs confirmed the biological and biochemical results obtained.