الفهرس | Only 14 pages are availabe for public view |
Abstract Pulmonary hyperteension is a frequent complication in thalassemias especially TI. The frequency of PHT in this study was 41.2% of which 57.1% were compound heterozygotes, 28.6% homozygotes and 14.3% heterozygotes. Patients with PHT had significant higher total serum bilirubin, higher LDH, serum ferritin, reticulocyte count. On the other hand, patients with PHT had significant lower levels of the initial RBCs , initial HB and initial HCT . There was a positive correlation between the genotype of the patients and LDH, mean HB and intial HB . Compound heterozygote patients had higher LDH and lower HB compared to other patients. Also, there was statistically significant Correlation between the genotypes of the patients and transfusion dependency, splenomegaly, and intake of iron chelators. RVSP of the patients was directly correlated with TSB and DSB ; and was inversely correlated with intial RBCs, HB, MCV and HCT. |