الفهرس 
Review of LiteratureOnly 14 pages are availabe for public view
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Abstract
Serum amyloid (SAA) is know best for its role during the acute phase response to an inflammatory stimulus such as infection, tissue injury, and trauma (Zhang, 2005).
The present study included 41 term neonates.
Classified into three groups: normal group (16 neonates), and the suspected group (25 neonates) which was subdivided into two subgroups according to clinical and biochemical evidence of infection and positive blood culture: (i) septic subgroup (17 neonates), which indicated that, there were 12 cases infected with gram negative organisms however there were 5 cases infected with gram positive organisms, and (ii) Non-septic subgroup (8 neonates).
The results and indicated a significant elevation in the activity of serum transaminases AST and ALT.
The SAA level increased significantly after 24 hours and decreased sharply reaching baseline after 48 hours in the septic group.
from the results, we can concluded that SAA is an early, highly sensitive and specific marker for the diagnosis of neonatal sepsis at birth, particularly if compared to diagnostic accuracy of CRP at this time. This can be useful in early initiation of antibiotic treatment.