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Abstract This work aimed at the study of the role of ultrasound elastography in differnation between benign and malignant breast lesions. The study conducted on20 patients with palpable breast lesions. Their ages ranged from 24 years to 67 years with a mean age of 46 years. All patients were subjected to full history taking,clinical examination, conventional gray scale ultrasound and ultrasound elastography. 17 patients were further evaluated by mammography, 7 patients did FNAC, 7 patients did core needle biopsy and 1 case did MRI mammography of the breast. Considering the pathological diagnosis in20 patients, there were 21 benign lesions and 15 malignantlesions. In currentstudy conventional Ultrasoundis very useful to demonstrate the characteristics of breast lesions including their number, size, shape, composition, texture, echogenicity, margins, and the presence of suspicious-appearing lymph nodes. We found a sensitivity of 80% and specificity 76% ofB mode US for breast lesions. Ultrasoundelastography, a noninvasive method for revealing the physical properties of a tissue, has been developed as an alternative to breast biopsy. The elastographic information is immediately available and superimposed in color on the B-mode image. Sonoelastography is, therefore, not more time consuming than conventional breast US In clinical practice, elastography is not used independently. According to our study, the benign lesions hadelasticity scores 1-3 and malignant lesions hadelasticity scores 4-5, the sensitivity and specificity of sonoelastographywere 80%,80.95 % respectively with PPV 75.0%, NPV 85.0% and accuracy 80.56 %. In currentstudy combinedB mode US and US elastographyshowedhigh sensitivity and specificity(86.4%, 90.4%) respectivelycompared to conventional US alone (80%, 76%) respectivelyor US elastography alone (80%,80.95 %)to differentiate between benign and malignant lesions In this studyaccording tostrain ratio measurements, the benign lesions produced a mean strainratio of1.64 ± 1.62 and malignant lesions produced a mean strain ratio of22.56 ± 26.2 with a cut of value <2. Thesensitivity and specificity of strain ratio between benign and malignant breast lesions were 93.33 % and 90.48 respectively. |