الفهرس | Only 14 pages are availabe for public view |
Abstract 4-Hydroxy-8-methyl-2(1H)quinolinone (1) was prepared and halogenated with phosphon1s oxychloride and/or phosphorus pentabromide to giVe 2,4-dihalo-8 - methylquinolines 2, 3 ,which were used to obtain many new azido, amino, hydrazino, and mercaptoquinoline, quinolinone and quinolinethione derivatives . Also , some new five membered heterocycles were synthesized, e.g. pyrazol yl, benzoimidazolyl , benzothiazolyl , triazoly l, thiadiazolyl , oxadiazolyl as substituents to the quinoline nucleus . Most of the new compounds are expected to have certain biological actiVIty. All the structures of the new products were verified on basis of their chemical behaviour , elemental and spectral analyses. |