الفهرس 
Chronic Kidney DiseaseOnly 14 pages are availabe for public view
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Abstract
Pain, depression, and sleep disorders are significant problems among CKD patients with varying degrees and intensities. In the current practice, little attention is paid to evaluate the prevalence and the causes of this problem with subsequent improper treatment of those patients. Pain is a multidimensional phenomenon with physical, psychological, and social components. Failure to treat pain adequately could be expected to lead to disruption in many aspects of life, such as functional status, mood and sleep. Accordingly, the present study was done to detect the prevalence of chronic pain, sleep disturbance, and depression in chronic kidney disease patients and possible predisposing factors. The study was conducted upon 200 patients classified as follows: - 50 CKD patients stage III. - 50 CKD patients stage IV. -50 CKD patients stage V. - 50 CKD patients stage V d. All patients were thoroughly interrogated and examined clinically, and were subjected to VON KORFF questionnaire, PITTSBURG SLEEP QUAILTY INDEX, Beck Depression Inventory, measurement of hemoglobin level (HB), serum albumin, serum creatinine, blood urea, serum Calcium (Ca), serum phosphorus (PO4), serum uric acid (UA), serum intact Parathormone (PTH), Ca X Po4 products, then data were collected and statistically analyzed. Based on the result of the current study it can be concluded that severity of chronic pain increases with conservative CKD management starting from stage 3-5, with highest sever pain percentage in stage 5, while patients on dialysis appear to have least sever chronic pain in comparable to stage 5 and 4. There was significant positive correlation between serum uric acid and chronic pain, Pain in our study was independently associated with higher PSQI (poor sleep) and higher BDI score (more depression). With conservative CKD management sleep quality worsening start from stage 3-5 with highest worst in stage 5, but with initiation of dialysis we found less poor sleep in stage 5D in comparable with stage 5 and 4. There was a significant positive correlation between lower albumin level, higher UA level, and higher PTH level and sleep quality. In our study we found that with conservative CKD management prevalence of severe depression increase starting from stage 3-5 with highest in CKD stage 5, while in stage 5D the prevalence of severe depression was less than in stage 5.