الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
This study was conducted on 50 patients who were secluded to receive deep irradiation to treat H&N Ca. The neck Ca cases constituted 96 % of our cases while head Ca cases constituted only 4%. The given RT course was either definitive in 34%, or adjuvant in 10 %, of our patients. The given RT needed adjuvant Ch T in 56%, and both were given as definitive modality in 8 % of patients, as adjuvant modality in 36%, and as palliative in 12 %. The included patients received their sittings in the Clinical Oncology and Nuclear Medicine Department of Alexandria University Hospital. The period of the study extended from October 2014 to January 2016.
All of the selected patients were subjected to a protocol of three subsequent otological assessments included a crucial tympanomertic evaluation supported with PTA. The 1st assessment was done before starting the RT course and should prove normal tympanograme and within normal PTA. The 2nd assessment was done immediately after the RT course. The 3rd assessment was done 6 months after RT course.
In the present study a trial was done to explore if the ET was lying in the field of radiation, rather directly in the beam portal of entry, would this induces any ET radiogenic changes in its function. ET dysfunction and OME are already reported to occur in patients receiving RT for H&N Ca. They are the commonest ear morbidities encountered in those patients, especially if the temporal bone was accidently lying in the portal of radiation beam entry, as cases of nasopharyngeal Ca and a like lesions. However, such lesions were found also to interfere mechanically with the ET function, and therefore their inclusion in previous studies resulted into improper evaluation and bias in result recording. By selecting patients prepared for H&N RT having Ca sites not in the vicinity of the ear, to avoid the ear being directly present in the way of beam entry, at the same time the ear present within the radiation field, we aimed to achieve more precise results. Consequently we were able to fulfill the aim of the present work being focusing on radiogenic effects on ET function in patients receiving H&N RT.