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Abstract Results: Significantly lower serum EGF level was I encountered in NEC preterms compared with control group (mean±SEM: 75.48±11.27 pg/ml vs. 268.3±43.90 pg/ml, I p<O.OOI). Neither clinical staging of NEC nor mode of I feeding had significantly influenced serum EGF level. At cut-off value of serum EGF of 130 pg/ml, NEC was I diagnosed with 86% sensitivity and 63% specificity. Serum EGF correlated positively (p<0.05) with each of gestational I age, birth weight, postnatal age, hemoglobin concentration I and platelet count. The peptide level partially recovered in survrvors of 7 days following the initial assessment I (p<0.05), but remained significantly lower than control (p<0.05). Final survivors among patients 6(17.1%), were I found to have higher EGF than those with fatal outcome (p<O.Ol). |