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العنوان
Comparative Study between Field-In-Field and
Intensity Modulated Radiotherapy Techniques
in Treatment of Breast Cancer /
المؤلف
Mohammed, Moaz Mohammed Zakaria.
هيئة الاعداد
باحث / Moaz Mohammed Zakaria Mohammed
مشرف / El-Sayed Mahmoud El-Sayed
مشرف / Amin El-Sayed Amin
مناقش / Amin El-Sayed Amin
تاريخ النشر
2016.
عدد الصفحات
186p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة أسيوط - كلية العلوم - Scienc
الفهرس
Only 14 pages are availabe for public view

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from 16

Abstract

Summary
This study aim to compare the planning efficiency between three
dimensional conformal radiotherapy (3D-CRT), inverse planned
intensity modulated radiotherapy (IP-IMRT) and field-in-field
forward planned intensity modulated radiotherapy (FIF-FP-IMRT)
techniques. In this work, twenty patients of breast cancer were
reviewed and categorized according to thickness of chest wall, into
three groups; small, medium and large.
In 3DCRT technique, plans were created by two tangential wedged opposing beams. All the studied groups had achieved good coverage of dose distribution; DR2%R value was in range of (109-110) % of prescribed dose and had achieved good conformity in all chest wall groups.
In IP-IMRT technique, two tangential beams and multiple
different beams directions were chosen to create IP-IMRT plans and
were inversely optimized; all plans had achieved good conformity
and homogeneity values. All IP-IMRT plans had DR2%R in range of
(107-108) % in medium and large chest wall group while increased it
to (111-114) % in small chest wall group.
In FiF-FP-IMRT technique, plans were created by combining two open fields with three to four segments in two tangential beam directions, DR2%R had range of (103-105) % of prescribed dose. It achieved good conformity similar to 3DCRT plans but less than IP-IMRT plans in all chest wall groups.
The dose delivered to heart, contra-lateral breast, lungs, cord and monitor units were compared among all plans. The obtained results showed that 3DCRT, Tangential IP-IMRT and FIF-FP-IMRT plans
had achieved good sparing and lowest dose of critical organs in all
chest wall groups. The D5% value of the heart was lower in FIF plans
than values with other plans in medium and large chest wall groups.
Also the Contra-lateral breast and cord had the lowest dose with
3DCRT, FIF-FP-IMRT and tangential IMRT plans in all chest wall
groups.
We can conclude that the obtained results showed that, FiF-FPIMRT
required less planning time, easy field placements and simple
quality assurance. In addition, it provided dosimetric advantages,
significantly reducing the size of the hot spot and minimally
improving the coverage of the target volume. So, we recommend
using this technique in treatment of breast cancer in Radiotherapy
hospitals in Egypt.