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العنوان
Screening for Prostate Specific Antigen in Various Types of Breast Tumor\
المؤلف
Muhamed,Marwa Fawzy Hasanein.
هيئة الاعداد
باحث / مروة فوزي حسنين محمد
مشرف / أحمد عثمان عجيزة
مشرف / عبد الرحمن بدر الدين عبد الغفار
مشرف / أحمد سامي أبو بكر
تاريخ النشر
2015.
عدد الصفحات
137p.;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
1/1/2015
مكان الإجازة
جامعة عين شمس - كلية العلوم - قسم الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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from 16

Abstract

Prostatic specific antigen (PSA) is a valuable tumor marker used for
diagnosis and management of prostate cancer. Recently, PSA has
been found in various female tissues and body fluids. Female breasts
both normal and abnormal, including cancerous tissues, can produce
PSA, and this production is regulated by androgens and progestins.
This study was applied on 65 women suffering from breast cancer,
31 of 65 have benign breast hyperplasia and 34 have malignant
breast cancer. Each group was divided into 2 groups, pre and
postmenopause, both groups were compared with 15 normal cases.
No significant difference in serum Total PSA concentration between
any of the studied cases. However there were different variations in
the distribution of PSA in the breast tumor tissue, with complete
absence of any presence of the PSA in the tissue samples of the
malignant after menopause patients.
Conclusion: PSA distributed in pre and postmenopausal female with
benign and malignant breast tissue, with absence of PSA in
postmenopausal female with malignant breast cancer