الفهرس 
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Abstract
Neonatal sepsis and its sequalae remains a significant cause of neonatal morbidity and mortality.
Calprotectin is a calcium and zinc binding protein. It accounts for 60% of neutrophils cytosol. In vitro studies show it has bacteriostatic and fungistatic properties. It is resistant to enzymatic degradation, and can be easily measured in faeces (Tibble et al., 2000
All neonates were subjected to full history taking stressing upon the risk factors for infection and through clinical examination for assessment of gestational age, birth weight and clinical signs of infection.
Serum calprotectin is significant high in preterm infant with neonatal sepsis its level correlated well with other laboratory markers of sepsis so serum calprotectin is accurate marker of sepsis in low birth weight neonate while fecal calprotectin may be use as marker for early evaluation of gastrointestinal condition in preterm infant.