الفهرس 
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Abstract
Miscarriage is the spontaneous loss of the conceptus before 20
weeks of gestation.
Recurrent pregnancy loss is also associated with several
autoimmune diseases, most notably systemic lupus erythematosus and
antiphospholipid syndrome and also thyroid autoimmunity.
The relation of thyroid autoimmunity to miscarriage is an
important issue that has attracted the interest of many investigators. Most
studies have shown a significant positive association between the
presence of thyroid autoantibodies and miscarriage rate.
Thyroperoxidase antibody (TPO Ab) positivity is considered as
high risk for pregnancy complications.
The present study aimed to evaluate the relationship between
thyroid autoimmunity and obstetrics outcome in women with recurrent
miscarriage.
This study included 200 patients aged from 21 to 35 years old,
less than 20 gestational weeks, divided into two groups:-
- Group (A): 100 pregnant patients with a history of miscarriage
twice or more.
- Group (B): 100 pregnant patients with no history of miscarriage
(control group).
Patients were recruited from the outpatient clinic of Department of
Obstetrics and Gynecology Menoufia University hospitals.
Patients with any uterine pathology or the presence anatomical or
functional cervical abnormalities or with any autoimmune diseases or
undergoing treatment for thyroid dysfunction must be excluded.